Orphenadrine is a prescription medication used mainly to relieve muscle pain and spasms. It’s often given alongside rest, physical therapy, or other treatments for musculoskeletal conditions.
What it does
Orphenadrine works by:
- Acting on the central nervous system to reduce muscle spasms
- Having anticholinergic effects (similar to some antihistamines), which can also contribute to pain relief
Common uses
- Acute muscle strains or injuries
- Back or neck pain with muscle spasm
- Sometimes used as an alternative when other muscle relaxants aren’t suitable

