How it works

Letrozole belongs to a class of drugs called aromatase inhibitors. It blocks an enzyme called aromatase, which the body uses to make estrogen.

• Less aromatase → less estrogen produced
• Lower estrogen levels can slow or stop the growth of some hormone-sensitive breast cancers.
• In fertility treatment, the temporary drop in estrogen causes the brain to release more follicle-stimulating hormone (FSH), which can stimulate ovulation.

Common uses

• Treatment of certain types of breast cancer after menopause.
• Fertility treatment to induce ovulation in women who are not ovulating regularly, such as some women with Polycystic Ovary Syndrome.