Dual Action Mechanism
- Paracetamol (The Messenger Blocker): It primarily works in the brain and spinal cord (central nervous system). It is thought to block chemical messengers called prostaglandins that signal pain and cause fever. By dampening these signals, it raises your overall pain threshold.
- Codeine (The Signal Interrupter): This is an opioid that acts as a “prodrug.” Once swallowed, your liver converts a portion of it into morphine. This morphine binds to “mu-opioid receptors” in your brain and spinal cord to physically interrupt pain signals traveling from your nerves to your brain. It also changes your emotional response to pain, making it feel less distressing.

